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Alternative Medicine, Psilocybin Mushrooms

Everything You Need To Know About Psychedelic Cannabis

Kenneth Bancale

by Kenneth Bancale

March 27, 2025 08:00 am ET Estimated Read Time: 7 Minutes
Fact checked by Precious Ileh
Marijuana Leave: Psychedelic effects

Cannabis is well known for its versatile effects, ranging from soothing relaxation to creative stimulation. But did you know that certain cannabis strains can induce a more profound psychedelic experience? While cannabis is not a traditional hallucinogen like lysergic acid diethylamide (LSD) or psilocybin mushrooms, some strains can deliver a unique, mind-expanding high that alters perception and heightens sensory experiences. This phenomenon can intrigue both experienced users looking to explore deeper realms of consciousness and those curious about the full potential of cannabis. Understanding how these psychedelic cannabis strains work, their effects, and how to use them safely is essential for an enjoyable experience. In this guide, we’ll cover everything you need to know about psychedelic cannabis, from the science behind its properties to the best strains to try.

Understanding Psychedelic Substances 

Psychedelic substances have been used for centuries for their profound impact on perception, consciousness, and mood. Traditionally, when people hear “psychedelics,” they often think of substances like psilocybin mushrooms (shrooms), LSD, and peyote. These substances are known for their ability to alter the state of the mind, leading to experiences such as visual and auditory hallucinations, changes in time perception, and deep introspection.

The primary mechanism through which psychedelics operate is their interaction with the brain’s serotonin receptors, specifically the 5-HT2A receptor. This interaction triggers changes in the brain’s connectivity, creating unique sensory experiences and, for some, a heightened state of awareness. Psychedelics can help with creativity, relaxation, and even therapeutic breakthroughs for conditions like Post-Traumatic Stress Disorder (PTSD) and depression when used responsibly under guidance.

Can Cannabis Have Psychedelic Properties? 

Cannabis is often categorized as a psychoactive substance due to its primary effects of altering mood, perception, and cognitive function. However, some strains, under certain conditions, can produce effects that verge on the psychedelic. Unlike classic hallucinogens, which produce vivid hallucinations, psychedelic cannabis strains can lead to more subtle effects, such as intensified sensory perceptions, shifts in time perception, and deep mental exploration.

Cannabis produces these effects primarily through its active compounds, notably THC (tetrahydrocannabinol). THC binds to the brain’s CB1 receptors, influencing the release of neurotransmitters and altering sensory perception. Terpenes, the aromatic compounds in cannabis, also play a role by modulating the overall experience through the “entourage effect.” This synergy between cannabinoids and terpenes can produce a more intense experience, sometimes referred to as a “psychedelic high.”

How Psychedelic Cannabis Affects Your Brain and Body 

The experience of consuming a psychedelic cannabis strain varies from person to person, largely influenced by factors such as the specific strain, dosage, the individual’s tolerance, and their mental state. Here’s what typically happens when someone consumes a strain with psychedelic properties:

  1. Heightened Sensory Perception: Users often report that colors appear more vivid, sounds are more pronounced, and tastes and smells are heightened. This sensory amplification can make ordinary experiences feel novel and immersive.
  2. Altered Sense of Time: For some, time may seem to slow down or speed up. A single minute might feel like an hour, or hours could pass by in what feels like seconds.
  3. Creative and Deep Thought Processes: Psychedelic strains can unlock creative thinking and inspire profound introspection. This can be particularly useful for artists, writers, and anyone looking for a new perspective on a problem.
  4. Potential Hallucinations: While not as common as with traditional psychedelics, high doses of certain cannabis strains can produce mild visual or auditory hallucinations, especially for those who are sensitive to THC.
  5. Physical Effects: Psychedelic cannabis strains can lead to an increased heart rate, a sensation of heavy limbs (often known as “couch lock”), and dry mouth or nausea. These effects are more pronounced with high-THC strains and can vary based on individual tolerance.

 

Cannabis Strains With Psychedelic Effects 

If you’re curious about trying a cannabis strain that leans toward a psychedelic experience, it’s essential to know which strains to look for and their unique effects. Here are some strains known for their potent, cerebral, and psychedelic properties:

Amnesia Haze

Amnesia Haze is a popular Sativa-dominant hybrid renowned for its energizing and mentally stimulating effects. This strain often produces an uplifting high that can lead to deep, creative thinking and a heightened sense of euphoria. Users may experience a shift in time perception and a feeling of mental clarity.

Durban Poison

As a pure Sativa strain, Durban Poison is famous for its invigorating and almost psychedelic head high. It provides a burst of energy and creativity, making it a favorite among those seeking a productive yet introspective experience. The heightened sensory perception it induces makes it an excellent choice for those looking to amplify their surroundings and thoughts.

LSD

Appropriately named after the hallucinogenic drug, LSD is an Indica-dominant hybrid that provides a powerful mental high. This strain can induce vivid sensory experiences and a dreamlike state that feels detached from reality. It’s known for its heavy psychoactive effects, which can sometimes be overwhelming for beginners.

Tickle Kush

Tickle Kush is a balanced hybrid that strikes a delicate balance between a euphoric high and deep relaxation. Users often report feeling both energized and blissful, making it a strain that can prompt creative thoughts and unique mental experiences.

Malawi

Malawi is a pure Sativa strain with a reputation for its powerful, long-lasting high. The psychoactive effects of Malawi are often intense and can lead to a deeply immersive, almost psychedelic experience. It’s best suited for experienced users who are familiar with the potential of a strong cerebral high.

 

Final Thoughts 

Exploring the world of psychedelic cannabis can be an eye-opening journey, whether you’re searching for creative inspiration, a unique recreational experience, or alternative ways to manage certain mental health conditions. While these strains can offer heightened sensory perceptions and an altered state of consciousness, it’s crucial to approach them with informed caution. Always consider your mental state, environment, and dosage to ensure a positive and safe experience.

If you’re interested in understanding how different cannabis strains could benefit your well-being, working with knowledgeable professionals can make all the difference. At Veriheal, we’re here to guide you through the nuances of medical cannabis use, help you find the right strains for your needs, and connect you with qualified medical professionals who understand cannabis as a form of therapy. Our goal is to provide you with the information and support needed to make empowered, safe decisions about your cannabis journey.

Frequently Asked Questions

What is the most psychedelic strain of cannabis? 

Strains like LSD, Malawi, and Amnesia Haze are among the most noted for their intense, psychedelic-like effects. These strains can induce unique mental and sensory experiences when consumed.

Is Sativa hallucinogenic? 

Sativa strains can be more stimulating and cerebral, sometimes producing sensory amplification that may feel hallucinogenic, especially at high doses or in sensitive individuals. However, true hallucinations are rare and more common with other types of psychedelics.

What is the difference between psychoactive and psychedelic? 

“Psychoactive” refers to any substance that alters the mind, affecting mood, perception, or cognition. “Psychedelic” is a subset of psychoactive substances that induce profound changes in perception, mood, and consciousness, often leading to visual or auditory hallucinations. Psychedelic cannabis is psychoactive, but not all psychoactive cannabis is considered psychedelic.

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