x
Ailments and Conditions, Medical Marijuana, Women's Health

Cannabis and Symptoms of PMS and PMDD: 7 Ways Marijuana Can Help

Kenneth Bancale

by Kenneth Bancale

March 10, 2025 08:00 am ET Estimated Read Time: 6 Minutes
Women having cramps: How cannabis can help improve PMS

Premenstrual syndrome (PMS) and premenstrual dysphoric disorder (PMDD) affect millions of women worldwide, leading to symptoms that can range from mild discomfort to debilitating pain and emotional distress. Traditional treatments include pain relievers, hormonal therapies, and antidepressants, but many women seek natural alternatives. Cannabis is emerging as a potential option for managing PMS and PMDD symptoms, offering relief from cramps, mood swings, fatigue, and more. But how exactly does it work? Let’s explore how marijuana can help with PMS and PMDD symptoms and which strains are best suited for relief.

Understanding PMS and the Menstrual Cycle 

PMS is a collection of physical and emotional symptoms that occur in the days leading up to menstruation, affecting around 75% of women of reproductive age (American College of Obstetricians and Gynecologists, 2021). Symptoms include bloating, irritability, fatigue, headaches, and body aches. PMDD is a more severe form of PMS, affecting about 3-8% of menstruating women. It is characterized by extreme mood swings, depression, and anxiety, significantly impacting daily life (Mishra, Elliott, & Marwaha, 2023).

Both PMS and PMDD are believed to be caused by hormonal fluctuations, particularly changes in estrogen and progesterone levels, which can affect neurotransmitters like serotonin and dopamine. These fluctuations can lead to physical discomfort and mood disturbances, making symptom management crucial for those affected.

How Cannabis Helps With Common Symptoms Of PMS

1. Bloating and Cramps 

Menstrual cramps are caused by prostaglandins, hormone-like substances that trigger uterine contractions. Cannabis, particularly strains high in cannabidiol (CBD), has anti-inflammatory properties that can help reduce cramping. Tetrahydrocannabinol (THC) can also help by altering pain perception, making cramps feel less intense. Some studies suggest that CBD relaxes uterine muscles, reducing the severity of contractions and bloating.

2. Mood Swings 

Hormonal fluctuations before menstruation can cause mood swings, irritability, and heightened emotional sensitivity. Cannabis interacts with the body’s endocannabinoid system (ECS), which regulates mood, stress response, and emotional stability. THC stimulates dopamine release, promoting feelings of happiness, while CBD has anxiolytic properties that help with stress and anxiety.

3. Fatigue and Insomnia 

Hormonal shifts can interfere with sleep patterns, causing fatigue during the day and difficulty sleeping at night. Indica-dominant cannabis strains are known for their sedative effects, helping users fall asleep faster and stay asleep longer. Additionally, THC can increase slow-wave sleep, which is crucial for physical recovery and overall restfulness.

4. Headaches and Migraines 

Estrogen fluctuations can trigger migraines in some women, leading to intense pain, nausea, and sensitivity to light. Research suggests that cannabis can help reduce the frequency and intensity of migraines by interacting with pain receptors and reducing inflammation. Many migraine sufferers report significant relief from THC-dominant strains (Sexton & Schuster, 2021).

5. PMDD 

PMDD can cause severe emotional and psychological symptoms, such as depression, anxiety, and irritability. Cannabis strains high in CBD may help regulate serotonin levels, improving mood stability. Additionally, THC’s euphoric effects can offer temporary relief from emotional distress, making PMDD symptoms more manageable.

6. Discomfort During Sex 

Hormonal changes can lead to vaginal dryness and discomfort during sex. Cannabis topicals, lubricants, and low-dose THC can enhance relaxation and increase blood flow, making sex more comfortable and enjoyable. Many women report heightened sensitivity and improved sexual satisfaction after using cannabis-infused products.

7. Acne 

Hormonal fluctuations often lead to breakouts before menstruation. CBD has anti-inflammatory and sebum-regulating properties, which may help reduce acne. Topical cannabis products can also help soothe irritated skin and promote overall skin health.

Best Strains For PMS 

Blue Dream (Hybrid)

Blue Dream is a well-balanced strain known for its uplifting effects and mild body relaxation. It helps with mood swings, anxiety, and mild pain relief, making it ideal for managing multiple PMS symptoms.

Granddaddy Purple (Indica)

This strain is popular for its sedative properties, making it a great choice for those experiencing insomnia and severe cramps. It promotes deep relaxation and pain relief.

Harlequin (CBD-Dominant Hybrid)

Harlequin has a high CBD content, making it ideal for inflammation, cramping, and mood stabilization. Its low THC levels ensure relief without strong psychoactive effects.

Girl Scout Cookies (Hybrid)

Known for its potent effects, this strain provides deep relaxation and euphoria, helping with pain, anxiety, and stress. It’s particularly beneficial for PMDD symptoms.

ACDC (High-CBD Strain)

ACDC is a CBD-dominant strain that is great for reducing inflammation and promoting relaxation without intoxication. It is ideal for those who want relief without the high.

Durban Poison (Sativa)

For those struggling with fatigue and low energy levels, Durban Poison provides an uplifting boost, making it easier to stay productive and alert.

White Widow (Hybrid)

White Widow offers a balanced experience, providing relief from pain while keeping the mind clear and focused. It is ideal for daytime use.

 

Final Thoughts 

For women dealing with PMS or PMDD, cannabis may offer a natural and effective alternative to traditional treatments. By targeting symptoms such as cramps, mood swings, fatigue, and headaches, cannabis can improve overall well-being during the menstrual cycle. However, it’s essential to find the right strain and dosage for your specific needs. If you’re considering medical cannabis, consulting with a healthcare professional or medical marijuana specialist—such as those at Veriheal—can help guide you toward the best treatment plan.

Frequently Asked Questions

Does cannabis affect female hormones? 

Cannabis interacts with the endocannabinoid system, which plays a role in hormone regulation. Some studies suggest THC and CBD can influence estrogen levels, but more research is needed to understand the long-term effects fully.

Will CBD help with PMS? 

Yes, CBD has anti-inflammatory and calming properties that can help alleviate PMS symptoms like cramps, anxiety, and mood swings. Many women use CBD products to manage menstrual discomfort without experiencing psychoactive effects.

Does smoking make PMDD worse? 

While cannabis can help with PMDD symptoms, some women may find that high doses of THC exacerbate anxiety or mood swings. Strains with balanced THC-to-CBD ratios or high-CBD content may be more suitable for managing PMDD effectively.

Note: The content on this page is for informational purposes only and is not intended to be professional medical advice. Do not attempt to self-diagnose or prescribe treatment based on the information provided. Always consult a physician before making any decision on the treatment of a medical condition. 

No Information on MarijuanaDoctors.Com should be used to diagnose, treat, prevent or cure any disease or condition. You can view our Full Disclaimer here.

Doctors Near You

See a doctor online and get approved in less than 30 minutes. In most states, you can get a medical card within 24 hours.

Dispensaries Near You

At Marijuana Doctors, we make it easy for dispensaries to service medical marijuana patients in the area.
plus sign

Are You A Doctor?

get listed here

Sign Up For Our Newsletter

Sign up for MarijuanaDoctors.com Free Monthly Newsletter! You Receive:

  • Exclusive Stories, News, Medical Reports & Articles, Fraud Alerts
  • Discounts, Coupons & Free Giveaways
  • Trusted Information